Juvenile nasopharyngeal angiofibroma is a pathologically benign yet locally aggressive and destructive vascular lesion of head and neck. The juvenile nasopharyngeal angiofibroma (JNA) is a highly Nasoangiofibroma youth is a highly vascularized tumor almost exclusively male. Juvenile nasopharyngeal angiofibromas (JNA) are a rare benign but locally aggressive vascular tumor. Epidemiology Juvenile nasopharyngeal angiofibromas.

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This makes it possible to precisely stage JNA. They develop at a slightly older age and occur more commonly in women.

Juvenile nasopharyngeal angiofibroma

Pterygopalatine fossa was invaded in 3 patients. Orbital decompression was done to resolve proptosis. Numerical sex chromosome aberrations in juvenile angiofibromas: This wngiofibroma was last edited on 29 Septemberat Accordingly, the treatment options, operative approach and prognosis can be determined. Primary radiation therapy for juvenile nasopharyngeal angiofibroma.

Endoscopic approach is an excellent tool in primary and recurrent JNA, it allows visualisation and precise removal of the lesion. JNA is benign but locally destructive.

Summary of signs and symptoms observed in the study. National Center for Biotechnology InformationU. If nasopharyngeal angiofibroma is suspected based on physical examination a smooth vascular submucosal mass in the posterior nasal cavity of beelia adolescent maleimaging studies such as CT or MRI should be performed.


Vascular fibroma of the nasopharynx naso-pharyngeal fibroma Arch Otolaryngol. Surgical excision was done with moderate intraoperative bleeding. Financial support and sponsorship Nil. Type I includes lesions fundamentally localized to the nasal cavity, paranasal sinus, nasopharynx, or pterygopalatine fossa. Non-small-cell lung carcinoma Squamous-cell carcinoma Adenocarcinoma Mucinous cystadenocarcinoma Large-cell lung carcinoma Rhabdoid carcinoma Sarcomatoid carcinoma Carcinoid Salivary gland—like carcinoma Adenosquamous carcinoma Papillary adenocarcinoma Giant-cell carcinoma.

Histopathology reveals a fibrocellular stroma with spindle cells and haphazard arrangement of collagen interspersed with an irregular vascular pattern. You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Advanced lesions with orbital and intracranial extension are difficult to treat and may recur often.

Endoscopic approach to juvenile nasopharyngeal angiofibroma: The exact site of origin is contentious as these masses usually present when they have reached considerable size.

Epistaxis was the most distressing symptom of all which made the patients to seek medical advice early. Two angioibroma case nos.

Nasopharyngeal angiofibroma – Wikipedia

Recent immunohistochemical and genetic studies throw some light on this topic. The main clinical presentation of JNA is unilateral nasal obstruction with or without epistaxis. Please review our privacy policy. Fisch classification, however, is currently accepted.

Juvenile nasopharyngeal angiofibroma

A year-old male patient presented with a painless, progressive swelling in the upper jaw since 2 weeks. The vascular supply to JNAs is primarily from distal internal maxillary artery branches, particularly the sphenopalatine, descending palatine and posterior superior alveolar branches. Histopathological examination revealed a proliferative connective tissue stroma interspersed with a thick vascular network.


Nasopharyngeal angiofibroma also called juvenile nasopharyngeal angiofibroma [1] [2] is a histologically benign but locally aggressive vascular tumor that grows in the nsaofaring of the nasal cavity. Genetic evidence for an androgen-dependent tumor?

Case 3 Case 3. Hippocrates [ 1 ] described the tumor in 5th century BC and Friedberg first used the term angiofibroma in [ 2 ].

Cases and figures Imaging differential diagnosis. This would better define the treatment strategy. Partial maxillectomy was done in case no 1 and 6. Conflicts of interest There are no conflicts angiovibroma interest. Everything was kept ready preoperatively to convert endoscopic approach to transpalatal approach as and when it is felt necessary. It most commonly affects adolescent males and may grow into fissures of the skull and may spread to adjacent structures.

Management of Juvenile Nasopharyngeal Angiofibroma: A Five Year Retrospective Study

Thank you for updating your details. Consistent expression of estrogen receptor beta. The 13 patients were given case numbers from 1 to