Free Online Library: La Hipervitaminosis A: una enfermedad multisistemica. by ” Revista de la Facultad de Farmacia”; Pharmaceuticals and cosmetics industries. Hypervitaminosis A is a disorder in which there is too much vitamin A in the body. English Translation, Synonyms, Definitions and Usage Examples of Spanish Word ‘hipervitaminosis A’.

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Vitamin A toxicity can occur with long-term ingestion of vitamin A supplements 10 times higher than the recommended daily dose; it can occur at lower hiprrvitaminosis in patients with chronic renal failure.

The dose over and above the RDA is among the narrowest of the vitamins and minerals. West Indian Med J. By contrast, absorption and storage of preformed vitamin A in animal liver or dietary supplements is efficient, and toxicity can occur if excessive quantities are ingested, especially in patients with renal failure.

The Medical Journal of Australia. She does not have any family history of hypercalcaemia or recurrent kidney stones.

La Hipervitaminosis A: una enfermedad multisistemica.

Her physical examination was normal except for mild lower extremities pitting oedema. This article explores 6 side effects of taking too much vitamin…. Absorption and storage in the liver of preformed vitamin A occur very efficiently until a pathologic condition develops.


By using this site, you agree to the Terms of Use and Privacy Policy. Most people improve simply by decreasing their intake of vitamin A.

Vitamin A Read more. Tissues are then able to take the retinol up as needed via cellular retinoid-binding protein 5. Hypercalcaemia can occasionally be associated with high levels of vitamin A but it is rare.

The Western Journal of Medicine. Elevated amounts of retinyl ester i. For those who develop complications, such as kidney or liver damage, their outlook will depend on the severity of the damage. However, in people with renal failure, IU daily can cause substantial damage 9. Calcification Calcification occurs when calcium builds up in areas of body tissue where calcium normally doesn’t exist.

Hypervitaminosis A – Wikipedia

A few months later, vitamin A and serum calcium levels returned to normal. Published online Hipfrvitaminosis Author information Copyright and License information Disclaimer. Stimulation of bone resorption by vitamin A has been reported to be independent of its effects on vitamin D. Candidate mechanisms for this increase include decreased hepatic uptake of vitamin A and the leaking of esters hipervitaminoss the bloodstream from saturated hepatic stellate cells.

Vitamin A deficiencies and excess.

Annals of the New York Academy of Sciences. If liver damage has progressed into fibrosis, synthesizing capacity is compromised and supplementation can replenish Hilervitaminosis.


Excess amounts of vitamin A are stored in your liver, and it accumulates over time. Toxicity results from ingesting too much preformed vitamin A from foods such as fish or animal liversupplements, or prescription medications and can be prevented by ingesting no more than the recommended daily amount.

Usually, supplements are involved. A genetic variance in tolerance to vitamin A intake may occur.

Taking too much vitamin A during pregnancy may cause abnormal development in the growing baby. Hypervitaminosis A results from excessive intake of preformed vitamin A. Vitamin A toxicity can be divided into acute, chronic or teratogenic.

Carotenoids themselves cannot produce toxicity. Vitamin A is a lipid-soluble compound referred to as retinoic acid.

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Headaches and rash are common in both forms of hipervitaminoeis illness. These treatments have been used to help treat or manage toxicity in animals. The toxic effects of vitamin A might be related to altered vitamin D metabolism, concurrent ingestion of substantial amounts of vitamin D, or binding of vitamin A to receptor heterodimers.